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View Project steph-affy-human-433773
Project Summary
Status: Public  
Publications: 4 Published
 		 
Project Detail Data Detail
Platform: Affymetrix MIAME Areas Compliance
Species: Human Array Design Detail true
Organ/Tissue Type: brain Experiment Detail true
Organ Region: Sample Detail false
Cell Type: layer III neurons Hybridization Detail false
Study Type: subclassification Measurement Detail false
Disease/Condition: Alzheimer's Disease
Replicates: 13
Expected Samples: 195 
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Available Actions
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Investigator Contact Detail
Name Dietrich A Stephan
Institution: TGen
Street Address: TGen
400 N. Fifth Street, Suite 1600
City, State/Province: Phoenix , AZ
Zip/Postal Code: 85004
Country: United States
Work Phone: 602-343-8427
Fax: 602-343-8440
E-mail: dstephan@tgen.org
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Proposal Detail
Grant: 5R01AG02319303
Status: Public
Service Type: Start to Finish Profiling
IRB: 123456
IRB date: 2006-07-07
Study Relevance:
Information about the genes that are preferentially expressed during the course of Alzheimer’s disease (AD) could improve our understanding of the molecular mechanisms involved in the pathogenesis of this common cause of cognitive impairment in older persons, provide new opportunities in the diagnosis, early detection, and tracking of this disorder, and provide novel targets for the discovery of interventions to treat and prevent this disorder. Information about the genes that are preferentially expressed in relationship to normal neurological aging could provide new information about the molecular mechanisms that are involved in normal age-related cognitive decline and a host of age-related neurological disorders, and they could provide novel targets for the discovery of interventions to mitigate some of these deleterious effects.
Hypothesis:
Scientific progress in the last few years has improved our understanding of AD and raised the hope of identifying treatments to halt the progression and prevent the onset of this disorder. For instance, researchers have begun to characterize the cascade of molecular events which lead to the major histopathological features of the disorder: neuritic plaques, which contain extra-cellular deposits of amyloid beta-peptides (Abeta); neurofibrillary tangles, which contain the hyperphosphorylated form of the intracellular, microtubule-associated protein, tau; and a loss of neurons and synapses. These molecular events provide targets for the development of promising new treatments. For example, A-beta has been postulated to trigger a cascade of events that are involved in the pathogenesis of AD. This proposal hopes to provide new information about the genes that are preferentially expressed in the development of AD histopathology, including the over-expression of APP, amyloid-induced neurotoxicity, and hyperphosphorylation of tau, as well as bring clarity to the metabolic abnormalities that seem to play a role in dementia and AD development and pathology.
Specific Aim:
Aim 1. Collect brain samples from three Alzheimer’s Disease Centers (ADCs) for subsequent gene expression profiling. Individuals will be stratified with respect to diagnostic groups (using both clinical and neuropathological criteria), age groups, and APOE genotype. 150 individual brains will be sampled from the Arizona ADC, the Duke University ADC, and the Washington University ADC. Miniscule sample sizes (200 um of sectioned tissue) from six brain regions that are histopathologically or metabolically relevant to AD and aging will be collected, ensuring that this proposal does not deplete the national resource. Frozen and fixed samples will be sent to Phoenix, sectioned in a standardized fashion, and then returned. Aim 2. Tissue heterogeneity will be eliminated prior to expression profiling by performing laser capture microscopy on all brain regions. Aim 3. Expression profile LCM-captured cells on the Affymetrix U133 Plus 2.0 array (~55,000 transcripts), and quickly provide these data to the community at large. Aim 4. Identify pathogenic cascades related to each of the clinico-pathologic correlates using unsupervised and supervised analyses coupled with a hypothesis-driven approach. Aim 5. Validation of the expression correlates at the protein and functional levels.
Experimental Procedure and Design:
We will perform LCM on 6 brain regions with about 14 biological replicates per brain region. The brain regions are as follows: 1) entorhinal cortex 2) hippocampus 3) medial temporal gyrus 4) posterior cingulate 5) superior frontal gyrus and 6) primary visual cortex. We will collect layer III pyramidal cells from the white matter in each region, isolate total RNA from LCMed cell lysates, and perform double round amplification of each sample for array analysis.
Quality Control Description:
We will have about 14 biological replicates per brain region.
Quality Control Types:
biological_replicate
Replicate Description:
14 replicates (separate cases) per brain region
Replicate Types:
biological_replicate
Experimental Factors:
Conditions that are tested in the experiment. At least one is required. Experimental factors are the independent variables in the experiment.
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Factor Name Description Factor Category
Brain Region We will compare gene expression in si... wait
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Project Samples  This section lists the samples that are associated with this project. Individual sample details can be viewed by clicking on the View Sample icon to the right of the sample. If samples are selectable for analysis or for addition to a virtual
Samples associated with this project.
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Action Button Key
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Name Description Bio-Source Extracts  
EC control 1 AD control EC control 1 1
EC control 2 AD control EC control 2 1
EC control 3 AD control EC control 3 1
EC control 4 AD control EC control 4 1
EC control 5 AD control EC control 5 1
EC control 6 AD control EC control 6 1
EC control 7 AD control EC control 7 1
EC control 8 AD control EC control 8 1
EC control 9 AD control EC control 9 1
EC control 10 AD control EC control 10 1
EC control 11 AD control EC control 11 1
EC control 12 AD control EC control 12 1
EC control 13 AD control EC control 13 1
HIP control 1 AD control HIP control 1 1
HIP control 2 AD control HIP control 2 1
HIP control 3 AD control HIP control 3 1
HIP control 4 AD control HIP control 4 1
HIP control 5 AD control HIP control 5 1
HIP control 6 AD control HIP control 6 1
HIP control 7 AD control HIP control 7 1
HIP control 8 AD control HIP control 8 1
HIP control 9 AD control HIP control 9 1
HIP control 10 AD control HIP control 10 1
HIP control 11 AD control HIP control 11 1
HIP control 12 AD control HIP control 12 1
HIP control 13 AD control HIP control 13 1
MTG control 1 AD control MTG control 1 1
MTG control 2 AD control MTG control 2 1
MTG control 3 AD control MTG control 3 1
MTG control 4 AD control MTG control 4 1
MTG control 5 AD control MTG control 5 1
MTG control 6 AD control MTG control 6 1
MTG control 7 AD control MTG control 7 1
MTG control 8 AD control MTG control 8 1
MTG control 9 AD control MTG control 9 1
MTG control 10 AD control MTG control 10 1
MTG control 11 AD control MTG control 11 1
MTG control 12 AD control MTG control 12 1
PC control 1 AD control PC control 1 1
PC control 2 AD control PC control 2 1
PC control 3 AD control PC control 3 1
PC control 4 AD control PC control 4 1
PC control 5 AD control PC control 5 1
PC control 6 AD control PC control 6 1
PC control 7 AD control PC control 7 1
PC control 8 AD control PC control 8 1
PC control 9 AD control PC control 9 1
PC control 10 AD control PC control 10 1
PC control 11 AD control PC control 11 1
PC control 12 AD control PC control 12 1
PC control 13 AD control PC control 13 1
SFG control 1 AD control SFG control 1 1
SFG control 2 AD control SFG control 2 1
SFG control 3 AD control SFG control 3 1
SFG control 4 AD control SFG control 4 1
SFG control 5 AD control SFG control 5 1
SFG control 6 AD control SFG control 6 1
SFG control 7 AD control SFG control 7 1
SFG control 8 AD control SFG control 8 1
SFG control 9 AD control SFG control 9 1
SFG control 10 AD control SFG control 10 1
SFG control 11 AD control SFG control 11 1
VCX control 1 AD control VCX control 1 1
VCX control 2 AD control VCX control 2 1
VCX control 3 AD control VCX control 3 1
VCX control 4 AD control VCX control 4 1
VCX control 5 AD control VCX control 5 1
VCX control 6 AD control VCX control 6 1
VCX control 7 AD control VCX control 7 1
VCX control 8 AD control VCX control 8 1
VCX control 9 AD control VCX control 9 1
VCX control 10 AD control VCX control 10 1
VCX control 11 AD control VCX control 11 1
VCX control 12 AD control VCX control 12 1
PC_affected_4 cortical layer III neurons PC_affected_4 1
EC_affected_1 cortical layer III neurons EC_affected_1 1
EC_affected_2 cortical layer III neurons EC_affected_2 1
EC_affected_3 cortical layer III neurons EC_affected_3 1
EC_affected_4 cortical layer III neurons EC_affected_4 1
SFG_affected_11 cortical layer III neurons SFG_affected_11 1
EC_affected_5 cortical layer III neurons EC_affected_5 1
EC_affected_6 cortical layer III neurons EC_affected_6 1
EC_affected_7 cortical layer III neurons EC_affected_7 1
EC_affected_8 cortical layer III neurons EC_affected_8 1
EC_affected_10 cortical layer III neurons EC_affected_10 1
HIP_affected_1 cortical layer III neurons HIP_affected_1 1
HIP_affected_2 cortical layer III neurons HIP_affected_2 1
HIP_affected_3 cortical layer III neurons HIP_affected_3 1
HIP_affected_4 cortical layer III neurons HIP_affected_4 1
HIP_affected_5 cortical layer III neurons HIP_affected_5 1
HIP_affected_6 cortical layer III neurons HIP_affected_6 1
HIP_affected_7 cortical layer III neurons HIP_affected_7 1
HIP_affected_8 cortical layer III neurons HIP_affected_8 1
HIP_affected_9 cortical layer III neurons HIP_affected_9 1
MTG_affected_1 cortical layer III neurons MTG_affected_1 1
MTG_affected_2 cortical layer III neurons MTG_affected_2 1
MTG_affected_3 cortical layer III neurons MTG_affected_3 1
MTG_affected_4 cortical layer III neurons MTG_affected_4 1
MTG_affected_5 cortical layer III neurons MTG_affected_5 1
MTG_affected_6 cortical layer III neurons MTG_affected_6 1
MTG_affected_7 cortical layer III neurons MTG_affected_7 1
MTG_affected_8 cortical layer III neurons MTG_affected_8 1
MTG_affected_9 cortical layer III neurons MTG_affected_9 1
MTG_affected_10 cortical layer III neurons MTG_affected_10 1
MTG_affected_11 cortical layer III neurons MTG_affected_11 1
MTG_affected_12 cortical layer III neurons MTG_affected_12 1
EC_affected_9 cortical layer III neurons EC_affected_9 1
PC_affected_1 cortical layer III neurons PC_affected_1 1
PC_affected_2 cortical layer III neurons PC_affected_2 1
PC_affected_3 cortical layer III neurons PC_affected_3 1
PC_affected_5 cortical layer III neurons PC_affected_5 1
PC_affected_6 cortical layer III neurons PC_affected_6 1
PC_affected_7 cortical layer III neurons PC_affected_7 1
PC_affected_8 cortical layer III neurons PC_affected_8 1
PC_affected_9 cortical layer III neurons PC_affected_9 1
SFG_affected_1 cortical layer III neurons SFG_affected_1 1
SFG_affected_2 cortical layer III neurons SFG_affected_2 1
SFG_affected_3 cortical layer III neurons SFG_affected_3 1
SFG_affected_4 cortical layer III neurons SFG_affected_4 1
SFG_affected_5 cortical layer III neurons SFG_affected_5 1
SFG_affected_6 cortical layer III neurons SFG_affected_6 1
SFG_affected_7 cortical layer III neurons SFG_affected_7 1
SFG_affected_8 cortical layer III neurons SFG_affected_8 1
SFG_affected_9 cortical layer III neurons SFG_affected_9 1
SFG_affected_10 cortical layer III neurons SFG_affected_10 1
SFG_affected_12 cortical layer III neurons SFG_affected_12 1
SFG_affected_13 cortical layer III neurons SFG_affected_13 1
SFG_affected_14 cortical layer III neurons SFG_affected_14 1
SFG_affected_15 cortical layer III neurons SFG_affected_15 1
SFG_affected_16 cortical layer III neurons SFG_affected_16 1
SFG_affected_17 cortical layer III neurons SFG_affected_17 1
SFG_affected_18 cortical layer III neurons SFG_affected_18 1
SFG_affected_19 cortical layer III neurons SFG_affected_19 1
SFG_affected_20 cortical layer III neurons SFG_affected_20 1
SFG_affected_21 cortical layer III neurons SFG_affected_21 1
SFG_affected_22 cortical layer III neurons SFG_affected_22 1
VCX_affected_1 cortical layer III neurons VCX_affected_1 1
VCX_affected_2 cortical layer III neurons VCX_affected_2 1
VCX_affected_3 cortical layer III neurons VCX_affected_3 1
VCX_affected_4 cortical layer III neurons VCX_affected_4 1
VCX_affected_5 cortical layer III neurons VCX_affected_5 1
VCX_affected_6 cortical layer III neurons VCX_affected_6 1
VCX_affected_7 cortical layer III neurons VCX_affected_7 1
VCX_affected_8 cortical layer III neurons VCX_affected_8 1
VCX_affected_9 cortical layer III neurons VCX_affected_9 1
VCX_affected_10 cortical layer III neurons VCX_affected_10 1
VCX_affected_11 cortical layer III neurons VCX_affected_11 1
VCX_affected_12 cortical layer III neurons VCX_affected_12 1
VCX_affected_13 cortical layer III neurons VCX_affected_13 1
VCX_affected_14 cortical layer III neurons VCX_affected_14 1
VCX_affected_15 cortical layer III neurons VCX_affected_15 1
VCX_affected_16 cortical layer III neurons VCX_affected_16 1
VCX_affected_17 cortical layer III neurons VCX_affected_17 1
MTG-NDAD-1 non-demented individuals wi... MTG-NDAD-1 1
EC-NDAD-1 non-demented individuals wi... EC-NDAD-1 1
EC-NDAD-2 non-demented individuals wi... EC-NDAD-2 1
EC-NDAD-3 non-demented individuals wi... EC-NDAD-3 1
EC-NDAD-4 non-demented individuals wi... EC-NDAD-4 1
EC-NDAD-5 non-demented individuals wi... EC-NDAD-5 1
EC-NDAD-6 non-demented individuals wi... EC-NDAD-6 1
HIP-NDAD-1 non-demented individuals wi... HIP-NDAD-1 1
HIP-NDAD-2 non-demented individuals wi... HIP-NDAD-2 1
HIP-NDAD-3 non-demented individuals wi... HIP-NDAD-3 1
HIP-NDAD-4 non-demented individuals wi... HIP-NDAD-4 1
HIP-NDAD-5 non-demented individuals wi... HIP-NDAD-5 1
HIP-NDAD-6 non-demented individuals wi... HIP-NDAD-6 1
MTG-NDAD-2 non-demented individuals wi... MTG-NDAD-2 1
MTG-NDAD-3 non-demented individuals wi... MTG-NDAD-3 1
MTG-NDAD-4 non-demented individuals wi... MTG-NDAD-4 1
MTG-NDAD-5 non-demented individuals wi... MTG-NDAD-5 1
MTG-NDAD-6 non-demented individuals wi... MTG-NDAD-6 1
PC-NDAD-1 non-demented individuals wi... PC-NDAD-1 1
PC-NDAD-2 non-demented individuals wi... PC-NDAD-2 1
PC-NDAD-3 non-demented individuals wi... PC-NDAD-3 1
PC-NDAD-4 non-demented individuals wi... PC-NDAD-4 1
PC-NDAD-5 non-demented individuals wi... PC-NDAD-5 1
SFG-NDAD-1 non-demented individuals wi... SFG-NDAD-1 1
SFG-NDAD-2 non-demented individuals wi... SFG-NDAD-2 1
SFG-NDAD-3 non-demented individuals wi... SFG-NDAD-3 1
SFG-NDAD-4 non-demented individuals wi... SFG-NDAD-4 1
SFG-NDAD-5 non-demented individuals wi... SFG-NDAD-5 1
SFG-NDAD-6 non-demented individuals wi... SFG-NDAD-6 1
VCX-NDAD-1 non-demented individuals wi... VCX-NDAD-1 1
VCX-NDAD-2 non-demented individuals wi... VCX-NDAD-2 1
VCX-NDAD-3 non-demented individuals wi... VCX-NDAD-3 1
VCX-NDAD-4 non-demented individuals wi... VCX-NDAD-4 1
VCX-NDAD-5 non-demented individuals wi... VCX-NDAD-5 1
HIP_affected_10 cortical layer III neurons HIP_affected_10 1
MTG_affected_13 cortical layer III neurons MTG_affected_13 1
MTG_affected_14 cortical layer III neurons MTG_affected_14 1
MTG_affected_15 cortical layer III neurons MTG_affected_15 1
MTG_affected_16 cortical layer III neurons MTG_affected_16 1
SFG_affected_23 cortical layer III neurons SFG_affected_23 1
VCX_affected_18 cortical layer III neurons VCX_affected_18 1
VCX_affected_19 cortical layer III neurons VCX_affected_19 1
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Project Hybridizations 

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View Hybridization View Hybridization  
Name Array Labeled Extract Hybridization Protocol  
Human Genome U133 Plus 2.0 Array_1_hyb Human Genome U133 Plus 2.0 Array_1 EC_control_1
Human Genome U133 Plus 2.0 Array_3_hyb Human Genome U133 Plus 2.0 Array_3 EC_control_2
Human Genome U133 Plus 2.0 Array_4_hyb Human Genome U133 Plus 2.0 Array_4 EC_control_3
Human Genome U133 Plus 2.0 Array_5_hyb Human Genome U133 Plus 2.0 Array_5 EC_control_4
Human Genome U133 Plus 2.0 Array_6_hyb Human Genome U133 Plus 2.0 Array_6 EC_control_5
Human Genome U133 Plus 2.0 Array_7_hyb Human Genome U133 Plus 2.0 Array_7 EC_control_6
Human Genome U133 Plus 2.0 Array_8_hyb Human Genome U133 Plus 2.0 Array_8 EC_control_7
Human Genome U133 Plus 2.0 Array_9_hyb Human Genome U133 Plus 2.0 Array_9 EC_control_8
Human Genome U133 Plus 2.0 Array_10_hyb Human Genome U133 Plus 2.0 Array_10 EC_control_9
Human Genome U133 Plus 2.0 Array_11_hyb Human Genome U133 Plus 2.0 Array_11 EC_control_10
Human Genome U133 Plus 2.0 Array_12_hyb Human Genome U133 Plus 2.0 Array_12 EC_control_11
Human Genome U133 Plus 2.0 Array_13_hyb Human Genome U133 Plus 2.0 Array_13 EC_control_12
Human Genome U133 Plus 2.0 Array_14_hyb Human Genome U133 Plus 2.0 Array_14 EC_control_13
Human Genome U133 Plus 2.0 Array_15_hyb Human Genome U133 Plus 2.0 Array_15 HIP_control_1
Human Genome U133 Plus 2.0 Array_16_hyb Human Genome U133 Plus 2.0 Array_16 HIP_control_2
Human Genome U133 Plus 2.0 Array_17_hyb Human Genome U133 Plus 2.0 Array_17 HIP_control_3
Human Genome U133 Plus 2.0 Array_18_hyb Human Genome U133 Plus 2.0 Array_18 HIP_control_4
Human Genome U133 Plus 2.0 Array_19_hyb Human Genome U133 Plus 2.0 Array_19 HIP_control_5
Human Genome U133 Plus 2.0 Array_20_hyb Human Genome U133 Plus 2.0 Array_20 HIP_control_6
Human Genome U133 Plus 2.0 Array_21_hyb Human Genome U133 Plus 2.0 Array_21 HIP_control_7
Human Genome U133 Plus 2.0 Array_22_hyb Human Genome U133 Plus 2.0 Array_22 HIP_control_8
Human Genome U133 Plus 2.0 Array_23_hyb Human Genome U133 Plus 2.0 Array_23 HIP_control_9
Human Genome U133 Plus 2.0 Array_24_hyb Human Genome U133 Plus 2.0 Array_24 HIP_control_10
Human Genome U133 Plus 2.0 Array_25_hyb Human Genome U133 Plus 2.0 Array_25 HIP_control_11
Human Genome U133 Plus 2.0 Array_26_hyb Human Genome U133 Plus 2.0 Array_26 HIP_control_12
Human Genome U133 Plus 2.0 Array_27_hyb Human Genome U133 Plus 2.0 Array_27 HIP_control_13
Human Genome U133 Plus 2.0 Array_28_hyb Human Genome U133 Plus 2.0 Array_28 MTG_control_1
Human Genome U133 Plus 2.0 Array_29_hyb Human Genome U133 Plus 2.0 Array_29 MTG_control_2
Human Genome U133 Plus 2.0 Array_30_hyb Human Genome U133 Plus 2.0 Array_30 MTG_control_3
Human Genome U133 Plus 2.0 Array_31_hyb Human Genome U133 Plus 2.0 Array_31 MTG_control_4
Human Genome U133 Plus 2.0 Array_32_hyb Human Genome U133 Plus 2.0 Array_32 MTG_control_5
Human Genome U133 Plus 2.0 Array_33_hyb Human Genome U133 Plus 2.0 Array_33 MTG_control_6
Human Genome U133 Plus 2.0 Array_34_hyb Human Genome U133 Plus 2.0 Array_34 MTG_control_7
Human Genome U133 Plus 2.0 Array_35_hyb Human Genome U133 Plus 2.0 Array_35 MTG_control_8
Human Genome U133 Plus 2.0 Array_36_hyb Human Genome U133 Plus 2.0 Array_36 MTG_control_9
Human Genome U133 Plus 2.0 Array_37_hyb Human Genome U133 Plus 2.0 Array_37 MTG_control_10
Human Genome U133 Plus 2.0 Array_38_hyb Human Genome U133 Plus 2.0 Array_38 MTG_control_11
Human Genome U133 Plus 2.0 Array_39_hyb Human Genome U133 Plus 2.0 Array_39 MTG_control_12
Human Genome U133 Plus 2.0 Array_40_hyb Human Genome U133 Plus 2.0 Array_40 PC_control_1
Human Genome U133 Plus 2.0 Array_41_hyb Human Genome U133 Plus 2.0 Array_41 PC_control_2
Human Genome U133 Plus 2.0 Array_42_hyb Human Genome U133 Plus 2.0 Array_42 PC_control_3
Human Genome U133 Plus 2.0 Array_43_hyb Human Genome U133 Plus 2.0 Array_43 PC_control_4
Human Genome U133 Plus 2.0 Array_44_hyb Human Genome U133 Plus 2.0 Array_44 PC_control_5
Human Genome U133 Plus 2.0 Array_45_hyb Human Genome U133 Plus 2.0 Array_45 PC_control_6
Human Genome U133 Plus 2.0 Array_46_hyb Human Genome U133 Plus 2.0 Array_46 PC_control_7
Human Genome U133 Plus 2.0 Array_47_hyb Human Genome U133 Plus 2.0 Array_47 PC_control_8
Human Genome U133 Plus 2.0 Array_48_hyb Human Genome U133 Plus 2.0 Array_48 PC_control_9
Human Genome U133 Plus 2.0 Array_49_hyb Human Genome U133 Plus 2.0 Array_49 PC_control_10
Human Genome U133 Plus 2.0 Array_50_hyb Human Genome U133 Plus 2.0 Array_50 PC_control_11
Human Genome U133 Plus 2.0 Array_51_hyb Human Genome U133 Plus 2.0 Array_51 PC_control_12
Human Genome U133 Plus 2.0 Array_52_hyb Human Genome U133 Plus 2.0 Array_52 PC_control_13
Human Genome U133 Plus 2.0 Array_53_hyb Human Genome U133 Plus 2.0 Array_53 SFG_control_1
Human Genome U133 Plus 2.0 Array_54_hyb Human Genome U133 Plus 2.0 Array_54 SFG_control_2
Human Genome U133 Plus 2.0 Array_55_hyb Human Genome U133 Plus 2.0 Array_55 SFG_control_3
Human Genome U133 Plus 2.0 Array_56_hyb Human Genome U133 Plus 2.0 Array_56 SFG_control_4
Human Genome U133 Plus 2.0 Array_57_hyb Human Genome U133 Plus 2.0 Array_57 SFG_control_5
Human Genome U133 Plus 2.0 Array_58_hyb Human Genome U133 Plus 2.0 Array_58 SFG_control_6
Human Genome U133 Plus 2.0 Array_59_hyb Human Genome U133 Plus 2.0 Array_59 SFG_control_7
Human Genome U133 Plus 2.0 Array_60_hyb Human Genome U133 Plus 2.0 Array_60 SFG_control_8
Human Genome U133 Plus 2.0 Array_61_hyb Human Genome U133 Plus 2.0 Array_61 SFG_control_9
Human Genome U133 Plus 2.0 Array_62_hyb Human Genome U133 Plus 2.0 Array_62 SFG_control_10
Human Genome U133 Plus 2.0 Array_63_hyb Human Genome U133 Plus 2.0 Array_63 SFG_control_11
Human Genome U133 Plus 2.0 Array_64_hyb Human Genome U133 Plus 2.0 Array_64 VCX_control_1
Human Genome U133 Plus 2.0 Array_65_hyb Human Genome U133 Plus 2.0 Array_65 VCX_control_2
Human Genome U133 Plus 2.0 Array_66_hyb Human Genome U133 Plus 2.0 Array_66 VCX_control_3
Human Genome U133 Plus 2.0 Array_67_hyb Human Genome U133 Plus 2.0 Array_67 VCX_control_4
Human Genome U133 Plus 2.0 Array_68_hyb Human Genome U133 Plus 2.0 Array_68 VCX_control_5
Human Genome U133 Plus 2.0 Array_69_hyb Human Genome U133 Plus 2.0 Array_69 VCX_control_6
Human Genome U133 Plus 2.0 Array_70_hyb Human Genome U133 Plus 2.0 Array_70 VCX_control_7
Human Genome U133 Plus 2.0 Array_71_hyb Human Genome U133 Plus 2.0 Array_71 VCX_control_8
Human Genome U133 Plus 2.0 Array_72_hyb Human Genome U133 Plus 2.0 Array_72 VCX_control_9
Human Genome U133 Plus 2.0 Array_73_hyb Human Genome U133 Plus 2.0 Array_73 VCX_control_10
Human Genome U133 Plus 2.0 Array_74_hyb Human Genome U133 Plus 2.0 Array_74 VCX_control_11
Human Genome U133 Plus 2.0 Array_75_hyb Human Genome U133 Plus 2.0 Array_75 VCX_control_12
Human Genome U133 Plus 2.0 Array_77_hyb Human Genome U133 Plus 2.0 Array_77 EC_affected_1_le1
Human Genome U133 Plus 2.0 Array_78_hyb Human Genome U133 Plus 2.0 Array_78 EC_affected_2_le1
Human Genome U133 Plus 2.0 Array_79_hyb Human Genome U133 Plus 2.0 Array_79 EC_affected_3_le1
Human Genome U133 Plus 2.0 Array_80_hyb Human Genome U133 Plus 2.0 Array_80 EC_affected_5_le1
Human Genome U133 Plus 2.0 Array_82_hyb Human Genome U133 Plus 2.0 Array_82 EC_affected_6_le1
Human Genome U133 Plus 2.0 Array_83_hyb Human Genome U133 Plus 2.0 Array_83 EC_affected_7_le1
Human Genome U133 Plus 2.0 Array_84_hyb Human Genome U133 Plus 2.0 Array_84 EC_affected_8_le1
Human Genome U133 Plus 2.0 Array_85_hyb Human Genome U133 Plus 2.0 Array_85 EC_affected_10_le1
Human Genome U133 Plus 2.0 Array_86_hyb Human Genome U133 Plus 2.0 Array_86 HIP_affected_1_e1_le1
Human Genome U133 Plus 2.0 Array_87_hyb Human Genome U133 Plus 2.0 Array_87 HIP_affected_2_e1_le1
Human Genome U133 Plus 2.0 Array_88_hyb Human Genome U133 Plus 2.0 Array_88 HIP_affected_3_e1_le1
Human Genome U133 Plus 2.0 Array_89_hyb Human Genome U133 Plus 2.0 Array_89 HIP_affected_4_e1_le1
Human Genome U133 Plus 2.0 Array_90_hyb Human Genome U133 Plus 2.0 Array_90 HIP_affected_5_e1_le1
Human Genome U133 Plus 2.0 Array_91_hyb Human Genome U133 Plus 2.0 Array_91 HIP_affected_6_e1_le1
Human Genome U133 Plus 2.0 Array_92_hyb Human Genome U133 Plus 2.0 Array_92 HIP_affected_7_e1_le1
Human Genome U133 Plus 2.0 Array_93_hyb Human Genome U133 Plus 2.0 Array_93 HIP_affected_8_e1_le1
Human Genome U133 Plus 2.0 Array_94_hyb Human Genome U133 Plus 2.0 Array_94 HIP_affected_9_e1_le1
Human Genome U133 Plus 2.0 Array_95_hyb Human Genome U133 Plus 2.0 Array_95 MTG_affected_1_e1_le1
Human Genome U133 Plus 2.0 Array_96_hyb Human Genome U133 Plus 2.0 Array_96 MTG_affected_2_e1_le1
Human Genome U133 Plus 2.0 Array_97_hyb Human Genome U133 Plus 2.0 Array_97 MTG_affected_3_e1_le1
Human Genome U133 Plus 2.0 Array_98_hyb Human Genome U133 Plus 2.0 Array_98 MTG_affected_4_e1_le1
Human Genome U133 Plus 2.0 Array_99_hyb Human Genome U133 Plus 2.0 Array_99 MTG_affected_5_e1_le1
Human Genome U133 Plus 2.0 Array_100_hyb Human Genome U133 Plus 2.0 Array_100 MTG_affected_6_e1_le1
Human Genome U133 Plus 2.0 Array_102_hyb Human Genome U133 Plus 2.0 Array_102 MTG_affected_7_e1_le1
Human Genome U133 Plus 2.0 Array_103_hyb Human Genome U133 Plus 2.0 Array_103 MTG_affected_8_e1_le1
Human Genome U133 Plus 2.0 Array_104_hyb Human Genome U133 Plus 2.0 Array_104 MTG_affected_9_e1_le1
Human Genome U133 Plus 2.0 Array_105_hyb Human Genome U133 Plus 2.0 Array_105 MTG_affected_10_e1_le1
Human Genome U133 Plus 2.0 Array_106_hyb Human Genome U133 Plus 2.0 Array_106 MTG_affected_11_e1_le1
Human Genome U133 Plus 2.0 Array_107_hyb Human Genome U133 Plus 2.0 Array_107 MTG_affected_12_e1_le1
Human Genome U133 Plus 2.0 Array_108_hyb Human Genome U133 Plus 2.0 Array_108 EC_affected_9_le1
Human Genome U133 Plus 2.0 Array_109_hyb Human Genome U133 Plus 2.0 Array_109 PC_affected_1_e1_le1
Human Genome U133 Plus 2.0 Array_110_hyb Human Genome U133 Plus 2.0 Array_110 PC_affected_2_e1_le1
Human Genome U133 Plus 2.0 Array_111_hyb Human Genome U133 Plus 2.0 Array_111 PC_affected_3_e1_le1
Human Genome U133 Plus 2.0 Array_112_hyb Human Genome U133 Plus 2.0 Array_112 PC_affected_4_e1_le1
Human Genome U133 Plus 2.0 Array_113_hyb Human Genome U133 Plus 2.0 Array_113 PC_affected_5_e1_le1
Human Genome U133 Plus 2.0 Array_114_hyb Human Genome U133 Plus 2.0 Array_114 PC_affected_6_e1_le1
Human Genome U133 Plus 2.0 Array_115_hyb Human Genome U133 Plus 2.0 Array_115 PC_affected_7_e1_le1
Human Genome U133 Plus 2.0 Array_116_hyb Human Genome U133 Plus 2.0 Array_116 PC_affected_8_e1_le1
Human Genome U133 Plus 2.0 Array_117_hyb Human Genome U133 Plus 2.0 Array_117 PC_affected_9_e1_le1
Human Genome U133 Plus 2.0 Array_118_hyb Human Genome U133 Plus 2.0 Array_118 SFG_affected_1_e1_le1
Human Genome U133 Plus 2.0 Array_119_hyb Human Genome U133 Plus 2.0 Array_119 SFG_affected_2_e1_le1
Human Genome U133 Plus 2.0 Array_120_hyb Human Genome U133 Plus 2.0 Array_120 SFG_affected_3_e1_le1
Human Genome U133 Plus 2.0 Array_121_hyb Human Genome U133 Plus 2.0 Array_121 SFG_affected_4_e1_le1
Human Genome U133 Plus 2.0 Array_122_hyb Human Genome U133 Plus 2.0 Array_122 SFG_affected_5_e1_le1
Human Genome U133 Plus 2.0 Array_123_hyb Human Genome U133 Plus 2.0 Array_123 SFG_affected_6_e1_le1
Human Genome U133 Plus 2.0 Array_124_hyb Human Genome U133 Plus 2.0 Array_124 SFG_affected_7_e1_le1
Human Genome U133 Plus 2.0 Array_125_hyb Human Genome U133 Plus 2.0 Array_125 SFG_affected_8_e1_le1
Human Genome U133 Plus 2.0 Array_126_hyb Human Genome U133 Plus 2.0 Array_126 SFG_affected_9_e1_le1
Human Genome U133 Plus 2.0 Array_127_hyb Human Genome U133 Plus 2.0 Array_127 SFG_affected_10_e1_le1
Human Genome U133 Plus 2.0 Array_128_hyb Human Genome U133 Plus 2.0 Array_128 SFG_affected_11_e1_le1
Human Genome U133 Plus 2.0 Array_129_hyb Human Genome U133 Plus 2.0 Array_129 SFG_affected_12_e1_le1
Human Genome U133 Plus 2.0 Array_130_hyb Human Genome U133 Plus 2.0 Array_130 SFG_affected_13_e1_le1
Human Genome U133 Plus 2.0 Array_131_hyb Human Genome U133 Plus 2.0 Array_131 SFG_affected_14_e1_le1
Human Genome U133 Plus 2.0 Array_132_hyb Human Genome U133 Plus 2.0 Array_132 SFG_affected_15_e1_le1
Human Genome U133 Plus 2.0 Array_133_hyb Human Genome U133 Plus 2.0 Array_133 SFG_affected_16_e1_le1
Human Genome U133 Plus 2.0 Array_134_hyb Human Genome U133 Plus 2.0 Array_134 SFG_affected_17_e1_le1
Human Genome U133 Plus 2.0 Array_135_hyb Human Genome U133 Plus 2.0 Array_135 SFG_affected_18_e1_le1
Human Genome U133 Plus 2.0 Array_136_hyb Human Genome U133 Plus 2.0 Array_136 SFG_affected_19_e1_le1
Human Genome U133 Plus 2.0 Array_137_hyb Human Genome U133 Plus 2.0 Array_137 SFG_affected_20_e1_le1
Human Genome U133 Plus 2.0 Array_138_hyb Human Genome U133 Plus 2.0 Array_138 SFG_affected_21_e1_le1
Human Genome U133 Plus 2.0 Array_139_hyb Human Genome U133 Plus 2.0 Array_139 SFG_affected_22_e1_le1
Human Genome U133 Plus 2.0 Array_140_hyb Human Genome U133 Plus 2.0 Array_140 VCX_affected_1_e1_le1
Human Genome U133 Plus 2.0 Array_141_hyb Human Genome U133 Plus 2.0 Array_141 VCX_affected_2_e1_le1
Human Genome U133 Plus 2.0 Array_142_hyb Human Genome U133 Plus 2.0 Array_142 VCX_affected_3_e1_le1
Human Genome U133 Plus 2.0 Array_143_hyb Human Genome U133 Plus 2.0 Array_143 VCX_affected_4_e1_le1
Human Genome U133 Plus 2.0 Array_144_hyb Human Genome U133 Plus 2.0 Array_144 VCX_affected_5_e1_le1
Human Genome U133 Plus 2.0 Array_145_hyb Human Genome U133 Plus 2.0 Array_145 VCX_affected_6_e1_le1
Human Genome U133 Plus 2.0 Array_146_hyb Human Genome U133 Plus 2.0 Array_146 VCX_affected_7_e1_le1
Human Genome U133 Plus 2.0 Array_147_hyb Human Genome U133 Plus 2.0 Array_147 VCX_affected_8_e1_le1
Human Genome U133 Plus 2.0 Array_148_hyb Human Genome U133 Plus 2.0 Array_148 VCX_affected_9_e1_le1
Human Genome U133 Plus 2.0 Array_149_hyb Human Genome U133 Plus 2.0 Array_149 VCX_affected_10_e1_le1
Human Genome U133 Plus 2.0 Array_150_hyb Human Genome U133 Plus 2.0 Array_150 VCX_affected_11_e1_le1
Human Genome U133 Plus 2.0 Array_151_hyb Human Genome U133 Plus 2.0 Array_151 VCX_affected_12_e1_le1
Human Genome U133 Plus 2.0 Array_152_hyb Human Genome U133 Plus 2.0 Array_152 VCX_affected_13_e1_le1
Human Genome U133 Plus 2.0 Array_153_hyb Human Genome U133 Plus 2.0 Array_153 VCX_affected_14_e1_le1
Human Genome U133 Plus 2.0 Array_154_hyb Human Genome U133 Plus 2.0 Array_154 VCX_affected_15_e1_le1
Human Genome U133 Plus 2.0 Array_155_hyb Human Genome U133 Plus 2.0 Array_155 VCX_affected_16_e1_le1
Human Genome U133 Plus 2.0 Array_156_hyb Human Genome U133 Plus 2.0 Array_156 VCX_affected_17_e1_le1
Human Genome U133 Plus 2.0 Array_157_hyb Human Genome U133 Plus 2.0 Array_157 HIP_affected_10
Human Genome U133 Plus 2.0 Array_158_hyb Human Genome U133 Plus 2.0 Array_158 MTG_affected_13
Human Genome U133 Plus 2.0 Array_159_hyb Human Genome U133 Plus 2.0 Array_159 MTG_affected_14
Human Genome U133 Plus 2.0 Array_160_hyb Human Genome U133 Plus 2.0 Array_160 MTG_affected_15
Human Genome U133 Plus 2.0 Array_161_hyb Human Genome U133 Plus 2.0 Array_161 MTG_affected_16
Human Genome U133 Plus 2.0 Array_162_hyb Human Genome U133 Plus 2.0 Array_162 SFG_affected_23
Human Genome U133 Plus 2.0 Array_163_hyb Human Genome U133 Plus 2.0 Array_163 VCX_affected_18
Human Genome U133 Plus 2.0 Array_164_hyb Human Genome U133 Plus 2.0 Array_164 VCX_affected_19
EC-NDAD-1 Human Genome U133 Plus 2.0 Array_2 EC-NDAD-1 Affymetrix
EC-NDAD-2 Human Genome U133 Plus 2.0 Array_76 EC-NDAD-2 Affymetrix
EC-NDAD-3 Human Genome U133 Plus 2.0 Array_167 EC-NDAD-3 Affymetrix
EC-NDAD-4 Human Genome U133 Plus 2.0 Array_168 EC-NDAD-4 Affymetrix
EC-NDAD-5 Human Genome U133 Plus 2.0 Array_169 EC-NDAD-5 Affymetrix
EC-NDAD-6 Human Genome U133 Plus 2.0 Array_170 EC-NDAD-6 Affymetrix
HIP-NDAD-1 Human Genome U133 Plus 2.0 Array_171 HIP-NDAD-1 Affymetrix
HIP-NDAD-2 Human Genome U133 Plus 2.0 Array_172 HIP-NDAD-2 Affymetrix
HIP-NDAD-3 Human Genome U133 Plus 2.0 Array_173 HIP-NDAD-3 Affymetrix
HIP-NDAD-4 Human Genome U133 Plus 2.0 Array_174 HIP-NDAD-4 Affymetrix
HIP-NDAD-5 Human Genome U133 Plus 2.0 Array_175 HIP-NDAD-5 Affymetrix
HIP-NDAD-6 Human Genome U133 Plus 2.0 Array_176 HIP-NDAD-6 Affymetrix
MTG-NDAD-1 Human Genome U133 Plus 2.0 Array_166 MTG-NDAD-1 Affymetrix
MTG-NDAD-2 Human Genome U133 Plus 2.0 Array_178 MTG-NDAD-2 Affymetrix
MTG-NDAD-3 Human Genome U133 Plus 2.0 Array_179 MTG-NDAD-3 Affymetrix
MTG-NDAD-4 Human Genome U133 Plus 2.0 Array_180 MTG-NDAD-4 Affymetrix
MTG-NDAD-5 Human Genome U133 Plus 2.0 Array_181 MTG-NDAD-5 Affymetrix
MTG-NDAD-6 Human Genome U133 Plus 2.0 Array_182 MTG-NDAD-6 Affymetrix
PC-NDAD-1 Human Genome U133 Plus 2.0 Array_183 PC-NDAD-1 Affymetrix
PC-NDAD-2 Human Genome U133 Plus 2.0 Array_184 PC-NDAD-2 Affymetrix
PC-NDAD-3 Human Genome U133 Plus 2.0 Array_185 PC-NDAD-3 Affymetrix
PC-NDAD-4 Human Genome U133 Plus 2.0 Array_186 PC-NDAD-4 Affymetrix
PC-NDAD-5 Human Genome U133 Plus 2.0 Array_187 PC-NDAD-5 Affymetrix
SFG-NDAD-1 Human Genome U133 Plus 2.0 Array_188 SFG-NDAD-1 Affymetrix
SFG-NDAD-2 Human Genome U133 Plus 2.0 Array_189 SFG-NDAD-2 Affymetrix
SFG-NDAD-3 Human Genome U133 Plus 2.0 Array_190 SFG-NDAD-3 Affymetrix
SFG-NDAD-4 Human Genome U133 Plus 2.0 Array_191 SFG-NDAD-4 Affymetrix
SFG-NDAD-5 Human Genome U133 Plus 2.0 Array_192 SFG-NDAD-5 Affymetrix
SFG-NDAD-6 Human Genome U133 Plus 2.0 Array_193 SFG-NDAD-6 Affymetrix
VCX-NDAD-1 Human Genome U133 Plus 2.0 Array_194 VCX-NDAD-1 Affymetrix
VCX-NDAD-2 Human Genome U133 Plus 2.0 Array_195 VCX-NDAD-2 Affymetrix
VCX-NDAD-3 Human Genome U133 Plus 2.0 Array_196 VCX-NDAD-3 Affymetrix
VCX-NDAD-4 Human Genome U133 Plus 2.0 Array_197 VCX-NDAD-4 Affymetrix
VCX-NDAD-5 Human Genome U133 Plus 2.0 Array_198 VCX-NDAD-5 Affymetrix
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